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Biological Information
Virology

Why cell characterisation is important in virology

Cell characterization in virology involves analyzing cell morphology, growth, viability, and susceptibility to viral infections. Techniques like nanoparticle tracking, interferometry, and zeta potential provide critical insights into host-virus interactions, aiding in the development of antiviral drugs, vaccines, and understanding viral pathogenesis and replication mechanisms.

Nanoparticle Tracking Analysis (NTA)

Nanoparticle Tracking Analysis (NTA) accurately sizes and counts viruses in solution by tracking their Brownian motion, providing crucial data for virology research, vaccine development, and understanding viral behaviour in biological fluids.

Nanoparticle Size and Concentration Analysis

Nanoparticle size and concentration analysis of viruses assesses their dimensions and quantity in solutions, essential for virology, vaccine development, and studying viral dynamics in biological environments.

Case study

A British-owned R&D laboratory aimed to optimise the production process of lentiviral vectors, critical for gene therapy and vaccine development. They integrated the Myriade Videodrop, a microfluidic-based platform for nanoparticle analysis, to enhance efficiency and quality control.The platform utilises microfluidic technology to measure size and concentration based on light scattering.

“Integration of our Videodrop streamlined the production process, reducing time and labor-intensive steps.”

The lab achieved significant success using the Myriade Videodrop for optimising lentiviral vector production. They proved the platform’s capability to enhance efficiency, ensuring quality, and accelerate advancements in gene therapy and vaccine development.

The integration of advanced nanoparticle analysis technologies like Videodrop is pivotal for driving breakthroughs in biopharmaceutical research and therapeutic applications.

Instruments to support analysis of viruses

nCS2 nanoparticle size analyser
nCS2
ARC nanoparticle size analyser
ARC
ViewSizer 3000
ViewSizer 3000
VideoDrop
VideoDrop
BeNano
BeNano 180 Zeta Pro

Applications to support the analysis of viruses

Virology
nCS2 Virology Application Note
Infectious Titer
Infections Titer Application Note
Viruses
Viruses Application Note
Phages and Lipids
Phages Application Note
Latex
Monoclonal Antibody Modified Latex Particles Application Note