Orflo
Moxi Z
Mini Automated Cell Counter Kit
- Produce repeatable cell counts with >95% accuracy in just 8 seconds
- Improve downstream results with better quality control
- Offers Precise Cell Counting
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Assess cell culture health without reagents or dyes
- Measure the smallest cells at very high concentrations
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Overview
Improve downstream results with better quality control.
Moxi Z is the only automated cell counter that combines the Coulter Principle typically used in high-end cell counters with a patented thin-film sensor technology to allow for highly accurate (> 95%) and repeatable particle counting and sizing for a broad range of cell types – from mammalian cells to cells as small as wine yeast and more. Since today’s workflows demand accurate quality control of samples, determining cell counts precisely has a significant impact on outcomes and downstream costs.
Produce repeatable, precise cell counting with >95% accuracy in just 8 seconds.
This ultra-small instrument uses patented microfluidic thin-film cassettes that enable automatic load and measure operation. The resulting single cell volumetric measurements are completely technique-independent. It provides the ideal alternative to the tedious manual counting associated with cytometers, or the inaccurate results associated with image-based automated cell counters (typical accuracies of 75-80%).
Assess cell culture health without reagents or dyes.
Moxi Z also automatically reports a unique cell health assessment index – MPI (Moxi Population Index) – without the need for reagents or dyes.MPI is a ratio of the cell population of interest relative to the entire particle distribution in that sample, factoring in dead cells that have shrunken or broken apart as well as other debris and contaminants in the sample. For monodisperse mammalian cultures this is closely correlated to the overall health of the sample.In the case of mixed cell populations, it’s provides an assessment of the relative fraction of the largest sized population in the sample. Unlike staining-based viability methods that focus on the uptake by dead cells and do not account for contaminants and other debris, MPI provides insight on the primary population of interest (based on size) and its relationship to ALL other particles in the sample.
Measure the smallest cells at very high concentrations.
Using the new Type S cassette, you can now accurately measure the smallest cells of any automated cell counter (down to 3um average diameter) at concentrations of up to 2.5e+6/ml. This means the new Type S cassette can measure Yeast (including wine yeast) and non-spherical particles down to 14 fL in volume.
Results in just 8 seconds
- Ultra-small and ultra-easy to use (no manual counting, no focusing of any kind)
- Complete, high-resolution cell size/count histogram
- Handles “de-aggregation” and coincidence events
- Post-processing/analysis of count distributions with user-adjustable regions/gates
- Assess cell health (MPI) without the need for reagents like Trypan blue
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Technical Specs
IdMXZ001
Included accessoriesInstrument only
AC power type110 VAC
ApplicationsCell Counting | Cell Size | Cell Health
Average Cell Diameter Range4 – 25 microns Type M | 3 – 20 microns Type S
Battery TypeRechargeable 3.7 V, 4400 mAh lithium ion
Cassette typesType M | Type S
CE CertificationYes
Cell Particle Concentration Range3,000 – 500,000 cells/mL Type M | 3,000 – 1,750,000 cells/mL Type S
Cell types testedHEK-293
HeLa
PC12
CD3+T
CHO-K1
Cos-7
HepG2
Hybridoma
Jurkat E6-1
K562
MCF7
Mesenchymal SC
Monocyte
Mouse ESC
NIH 3T3
PBMC (cultured)
Red Blood Cells (RBC)
L5178y
C. albicans (Yeast)
S. cerevisiae Vin 13 (Yeast)
S. cerevisiae X5 (Yeast)
Wine Yeast (natural fermentaion)
S.cerevisiae (Baker’s Yeast
Safale US-05 YeastData output formats.csv format (Orflo MoxiChart or Microsoft Excel)
In British units1.5 lbs
Intended use statementFor Research Use Only. Product is not for use in diagnostic procedures
Measurable dynamic range4- 34 microns Type M
3 -26 microns Type SMeasurement time15 seconds Type S
10 seconds Type MMPI cell healthYes
Number of detection channels flow parameters1
Overall dimensions7.6 L x 4.3 W x 2.8 H (in)
Particle size detection methodImpedimetric (Coulter Principle)
PlatformNo
Pre-programmed testsNone
Sample typeMammalian Cells|Large Yeast|Large Algae|Protozoa Type M
Mammalian Cells|Most Yeast|Small Algae|Small Protozoa Type SSample volume75 µL
Supported connectivityUSB on-the-go; PC or Mac compatible; requires Windows XP, Windows Vista, Windows 7, or Mac OS X operating system
Useable cell volume34 – 20,580 fL Type M
14 – 4,200 fL Type SWeight0.68 kg
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How it works
Electronic current is passed through a small hole (Cell Sensing Zone) in a thin-film membrane. Cells flow substantially single file through the CSZ causing momentary increases in measured voltage that are directly proportional to cell or particle volume. Thousands of cells are measured during a single test and the size of each cell is plotted and saved in histogram format. Total volumetric counts are determined by precisely measuring the volume of fluid being analysed.
Insert cassette into Moxi Z.
Pipette 75 μL sample into cassette. Touch Screen.
Finished! Automatic, hands-free measurement in just 8 seconds.
Note: Each cassette holds 2 tests. When Sample 1 is complete, simply re-insert other end of cassette into MoxiZ, and load Sample 2.
Data
Data For each measurement, a complete histogram is displayed as well as cell count, average cell size and Moxi Population Index. The raw waveform from the most recent cell count, containing each cell spike, is also stored on the Moxi Z and can be both viewed on the Moxi Z and uploaded to the PC for additional analysis. The Moxi Z also performs sophisticated curve fitting analysis to more accurately determine cell counts in the event of overlapping populations of cells (or debris), significantly improving the accuracy of the volumetric counts produced by the Moxi Z. Data for 500 samples may be stored on the unit. All data can be transferred to a PC/Mac via Bluetooth. No special software is required for the PC since date files are Excel®-compatible. Sophisticated PC/Mac compatible analys software is included with each Moxi Z. Cell health may be assessed by comparing differences in histograms from culture to culture.
Instructional Videos
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Applications
Blood Cells
Monitoring Cell Health
Algal Growth
Yeast Monitoring
Not sure if it’s the right instrument?
No worries, send us a sample and we will test it for you
Send a sample-
Outstanding service
I have been using Meritics for a number of years and they always provide outstanding service and support.
They have a rapid response turnarounds and are very knowledgeable of the techniques and products they provide.LeanneB-375
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Good service, very helpful
We use Meritics for the PM service and installation of all our FlowCams . Megan has been coming to our site for a number of years. She is very efficient in her work, but most of all Megan is very helpful. We have had issues with one of instruments after the install and Megan did her utmost to try and solve it while on site, even though it wasn’t solved Megan has been in contact with the supplier of the instrument to try and solve this problem for us.
SophieH-2201
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Job done in a friendly manner
Booking engineer visits is always easy. David Lowe, Meritics engineer is always very friendly.
ThierryN
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Service/calibration visit
Excellent service, arrived on time, polite, friendly and informative.
NathamM-270
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5 Stars
Excellent service from an excellent company. Would recommend them to anyone.
BarryH-480
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Good Service
David, our service engineer as usual was good at communicating and setting up the recent service appointment, he arrived on time, did the service promptly and informed me of any problems. Friendly and helpful
TomA-446
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Superb and prompt service
I have used this company through the laboratory I work for frequently. We specialise in soil analysis, and Meritics were chosen as they have extensive knowledge of the instruments we use. We have several laser particle diffraction analysers with a service contract, and service is always very prompt and meticulous….
JamesG-2483
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Good experience over two years
Meritics have covered the annual servicing of our Multisizer 4e instrument since we purchased it from them just over two years ago. The application scientist who performed the servicing was friendly, knowledgeable, and extremely helpful, happily answering a barrage of questions about how best to use and maintain the instrument. All my interactions with Meritics staff have been positive. I would happily recommend them.
RajG-62
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Fully committed to customer service
Service second to none, both units serviced and all questions answers by engineer while on site.
RichardA-786
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Highly recommend Meritics for equipment purchases and aftercare services
After owning one of our instruments for over 8 Years which was purchased from Meritics, it suffered its first breakdown. Upon contacting Meritics, I was instantly put through to an engineer who was very helpful. Upon inspection of the manual, it was decided that it would be more cost effective to have a Meritics engineer visit. The Meritics staff were very communicative and kept me up to date.
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Excellent Service
Lovely, friendly and extremely helpful. David and his team are always on call with advise and are very easy to work with and are always happy to help.
NaomiT-64
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Service of lab equipment
Excellent service. Friendly and professional service was provided in a timely manner to the expected standard.
NathanM-270
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Excellent
Excellent communication. Updates given well in advance. Very polite staff and engineers.
NathanM-270
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Multisizer 4e install at pharmaceutical company
2 people helped with the install of a Multisizer 4e. They were both very professional and friendly, answering any questions that I had. The installation was quick and the attention to good documentation practice was exceptional.
Chloel-9
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Service of Beckman Coulter instruments
Always a pleasure to welcome the Meritics service engineer, who is knowledgeable, personable and extremely competent.
NeilT-394
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Professional
Friendly and collaborative staff, provided a very good service.
SamK-403
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Professional, Customer-oriented, fast service
We had issues with one of the aperture tubes provided by Meritics on a Friday afternoon, while very pressed for a review deadline. Meritics handled our inquiries very fast and professionally and helped us out by shipping us their spare tube to use in the mean time free of charge, while we waited for our new tube to arrive. Communication was very pleasant.
VeerleB
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Very helpful and prompt
I emailed for some technical help and also to get some spares and both the engineer (David) and purchasing (Sophie) were very prompt to respond and helpful. We do have a service contract but I appreciated being able to email the engineer directly.
AlexH-474
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Excellent Service
Used Meritics to conduct particle size distribution by laser diffraction. Service as last time, is very quick, well priced and professional.
I would highly recommend
GavinR-101
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Excellent and Friendly Service
Always a pleasure to deal with the people at Meritics Ltd. They understand the importance of our work and the fact that our research projects have deadlines that need to be met. Consequently, problems are dealt with very quickly and professionally and they are willing to go that one step further to make sure their supply chain problems don’t become our problems. Thank you to the team for their support. It is greatly appreciated.
JanetH-255