Characterising Iron Dextran Preparation with the BeNano 90
In this application note, the BeNano 90 was used to characterize two iron dextran injections, a commercially available one and a R&D stage one. Size differences were successfully distinguished, and the presence of aggregates in the R&D sample was ascertained. With regards to the injection preparations, particular attention needs to be paid to the formation of aggregates, due to their significant effect on the drug stability, efficacy, and immune response. Hence, the BeNano 90 with its excellent sensitivity for aggregates or large particles will be extremely useful and convenient as a research tool for injection preparation.
