Yokogawa Fluid Imaging Technologies
FlowCam Nano

Flow Imaging Microscopy

  • Measurement range 300 nm to 2 µm
  • Submicron particle imaging
  • Biopharmaceutical and other materials applications

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Beckman Coulter LS 13 320 XR Laser Diffraction Particle Size Analyser 21 CFR Part 11

High-resolution images to detect and identify submicron particle types

FlowCam Nano provides dynamic image analysis of submicron particles from 300 nm to 2 µm, bridging the gap between traditional flow imaging microscopy and other particle analysis techniques.

Use FlowCam Nano for early detection of aggregates and contaminant monitoring for protein formulations, nano-drug delivery systems, characterization of bacteria, bioprocess monitoring, and materials characterization.

  • Overview

    FlowCam Nano is a flow imaging microscope for submicron particle imaging in biopharmaceutical and other materials applications. Its advanced optical imaging capabilities enable detection and morphological analysis of the smallest particles observable using light microscopy.

    Detect submicron-sized particles including protein aggregates and small oligomers of drug delivery vehicles like LNPs and exosomes to proactively improve product stability and quality—even before larger particles are present.

  • Technical Specs

    Measurement size

    Flow imaging and particle sizing from 300 nm to 2 µm using oil immersion with 40X magnification
    Minimum sample volume

    Minimum sample volume of 100 µL
    Sample flow rate

    Sample flow rate up to 25 μL/minute
    Camera

    High-resolution monochrome camera
    Compatible with

    Compatible with aqueous solvents for analysis in native buffers
    User friendly

    Ease of use with disposable flow cells and autofocus technology

  • Benefits

    • Detect early API aggregate formation and other forms of sample degradation that are prone to generating larger subvisible and visible particles
    • Acquire high-resolution images to detect and identify submicron particle types to inform product development and monitor product quality
    • Obtain size, morphology, and relative concentrations of particles that are too small to be detected by traditional Flow Imaging Microscopy
    • Experience integrated, industry-leading VisualSpreadsheet software with the unique ability to image, classify, and characterize nanoparticles in real-time with an easy-to-use interface

  • Applications

    Environmental Research

    Protein Therapeutics

    Advanced Materials

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  • Outstanding service

    I have been using Meritics for a number of years and they always provide outstanding service and support.
    They have a rapid response turnarounds and are very knowledgeable of the techniques and products they provide.

    LeanneB-375

  • Good service, very helpful

    We use Meritics for the PM service and installation of all our FlowCams . Megan has been coming to our site for a number of years. She is very efficient in her work, but most of all Megan is very helpful. We have had issues with one of instruments after the install and Megan did her utmost to try and solve it while on site, even though it wasn’t solved Megan has been in contact with the supplier of the instrument to try and solve this problem for us.

    SophieH-2201

  • Job done in a friendly manner

    Booking engineer visits is always easy. David Lowe, Meritics engineer is always very friendly.

    ThierryN

  • Service/calibration visit

    Excellent service, arrived on time, polite, friendly and informative.

    NathamM-270

  • 5 Stars

    Excellent service from an excellent company. Would recommend them to anyone.

    BarryH-480

  • Good Service

    David, our service engineer as usual was good at communicating and setting up the recent service appointment, he arrived on time, did the service promptly and informed me of any problems. Friendly and helpful

    TomA-446

  • Superb and prompt service

    I have used this company through the laboratory I work for frequently. We specialise in soil analysis, and Meritics were chosen as they have extensive knowledge of the instruments we use. We have several laser particle diffraction analysers with a service contract, and service is always very prompt and meticulous….

    JamesG-2483

  • Good experience over two years

    Meritics have covered the annual servicing of our Multisizer 4e instrument since we purchased it from them just over two years ago. The application scientist who performed the servicing was friendly, knowledgeable, and extremely helpful, happily answering a barrage of questions about how best to use and maintain the instrument. All my interactions with Meritics staff have been positive. I would happily recommend them.

    RajG-62

  • Fully committed to customer service

    Service second to none, both units serviced and all questions answers by engineer while on site.

    RichardA-786

  • Highly recommend Meritics for equipment purchases and aftercare services

    After owning one of our instruments for over 8 Years which was purchased from Meritics, it suffered its first breakdown. Upon contacting Meritics, I was instantly put through to an engineer who was very helpful. Upon inspection of the manual, it was decided that it would be more cost effective to have a Meritics engineer visit. The Meritics staff were very communicative and kept me up to date.

  • Excellent Service

    Lovely, friendly and extremely helpful. David and his team are always on call with advise and are very easy to work with and are always happy to help.

    NaomiT-64

  • Service of lab equipment

    Excellent service. Friendly and professional service was provided in a timely manner to the expected standard.

    NathanM-270

  • Excellent

    Excellent communication. Updates given well in advance. Very polite staff and engineers.

    NathanM-270

  • Multisizer 4e install at pharmaceutical company

    2 people helped with the install of a Multisizer 4e. They were both very professional and friendly, answering any questions that I had. The installation was quick and the attention to good documentation practice was exceptional.

    Chloel-9

  • Service of Beckman Coulter instruments

    Always a pleasure to welcome the Meritics service engineer, who is knowledgeable, personable and extremely competent.

    NeilT-394

  • Professional

    Friendly and collaborative staff, provided a very good service.

    SamK-403

  • Professional, Customer-oriented, fast service

    We had issues with one of the aperture tubes provided by Meritics on a Friday afternoon, while very pressed for a review deadline. Meritics handled our inquiries very fast and professionally and helped us out by shipping us their spare tube to use in the mean time free of charge, while we waited for our new tube to arrive. Communication was very pleasant.

    VeerleB

  • Very helpful and prompt

    I emailed for some technical help and also to get some spares and both the engineer (David) and purchasing (Sophie) were very prompt to respond and helpful. We do have a service contract but I appreciated being able to email the engineer directly.

    AlexH-474

  • Excellent Service

    Used Meritics to conduct particle size distribution by laser diffraction. Service as last time, is very quick, well priced and professional.

    I would highly recommend

    GavinR-101

  • Excellent and Friendly Service

    Always a pleasure to deal with the people at Meritics Ltd. They understand the importance of our work and the fact that our research projects have deadlines that need to be met. Consequently, problems are dealt with very quickly and professionally and they are willing to go that one step further to make sure their supply chain problems don’t become our problems. Thank you to the team for their support. It is greatly appreciated.

    JanetH-255